Exforge HCT 5/12.5/160mg is a combination medication used to treat high blood pressure (hypertension). Each tablet contains three active ingredients: amlodipine besylate, hydrochlorothiazide, and valsartan. Amlodipine works by relaxing blood vessels, making it easier for the heart to pump blood. Hydrochlorothiazide helps eliminate excess salt and water from the body, reducing blood volume and pressure. Valsartan blocks the action of certain natural substances that tighten blood vessels, allowing for smoother blood flow. This combination effectively lowers blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.